DNA launched suicidal flaviviruses as therapeutic vaccine candidates

DNA launched suicidal flaviviruses as therapeutic vaccine candidates

Research background
Chronic liver disease, resulting from Hepatitis B virus (HBV), Hepatitis D virus (HDV), or Hepatitis
C virus (HCV) infections, contributes to a major health burden worldwide. The relatively high
cost of the HCV treatment brings concerns about the accessibility, especially in the developing
countries. Hence, there exists a need for cost effect interventions with high efficiency. The use
of DNA prime-viral vector has been validated in prime-boost vaccination. The use of Flavivirus
subgenomic replicons as DNA based vaccine will provide excellent stability and high expression
of the vaccine candidate genes in combination with immune activation…..

Combination therapy of tumors

Combination therapy of tumors

Since it is common practice to combine irradiation of tumours in humans with drug treatment we have developed procedures that works on nude mice xenotransplanted with human tumour cells. The figure below shows an example in which HCT116/GFP tumours responded to...

Kanceras HDAC6-projekt tilldelas anslag från Vinnova

Pressmeddelande Stockholm 2015-06-12 Kanceras HDAC6-projekt tilldelas anslag från Vinnova Kancera har av Sveriges innovationsmyndighet VINNOVA tilldelats ett anslag om totalt 2,000,000 kronor riktat till projekt som kan utvecklas till nya starka innovationer....